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Test ID: HGB_Q Hemoglobin, Qualitative, Urine

Reporting Name

Hemoglobin, QL, U

Useful For

Screening for hematuria, myoglobinuria, or intravascular hemolysis

Specimen Type


Specimen Required

Container/Tube: Plastic, 10-mL urine tube (T068)

Specimen Volume: 5 mL

Collection Instructions: Collect a random urine specimen.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated 72 hours

Reference Values

Appearance (internal specimens only): normal

Hemoglobin: negative

RBCs (internal specimens only): 0-2 rbcs/hpf

Test Classification

This test has been cleared, approved or is exempt by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
HGB_Q Hemoglobin, QL, U 5794-3


Result ID Test Result Name Result LOINC Value
APP4 Appearance 5767-9
HGBQL Hemoglobin, QL 5794-3
RBC3 RBC 46419-8

Clinical Information

Free hemoglobin (Hgb) in urine usually is the result of lysis of RBCs present in the urine due to bleeding into the urinary tract (kidney, ureters, bladder). Less commonly, intravascular hemolysis (eg, transfusion reaction, hemolytic anemia, paroxysmal hemoglobinuria) may result in excretion of free Hgb from blood into urine.


Injury to skeletal or cardiac muscle results in the release of myoglobin, which also is detected by this assay. Conditions associated with myoglobinuria include hereditary myoglobinuria, phosphorylase deficiency, sporadic myoglobinuria, exertional myoglobinuria in untrained individuals, crush syndrome, myocardial infarction, myoglobinuria of progressive muscle disease, and heat injury.


Free hemoglobin (Hgb), in the presence of RBCs, indicates bleeding into the urinary tract.


Free Hgb, in the absence of RBCs, is consistent with intravascular hemolysis.

Note: RBCs may be missed if lysis occurred prior to analysis; the absence of RBCs should be confirmed by examining a fresh specimen.


The test is equally sensitive to hemoglobin and to myoglobin. The presence of myoglobin may be confirmed by MYOU / Myoglobin, Urine.

Clinical Reference

Fairbanks, V.F. and Klee G.G., Textbook of Clinical Chemistry 1986, Chapter 15, p 1562

Analytic Time

Same day/1 day

Method Name



If not ordering electronically, complete, print, and send a Benign Hematology Test Request Form (T755) with the specimen.

Mayo Clinic Laboratories | Hematology Catalog Additional Information: